Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss

CMP-Neu5Ac hydroxylase (Cmah) disruption caused several abnormalities and diseases including hearing loss in old age. However, underling molecular mechanisms that give rise to age-related hearing loss (AHL) in Cmah-null mouse are still obscure. In this study, Cmah-null mice showed age-related declin...

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Detalles Bibliográficos
Autores principales: Kwon, Deug-Nam, Park, Woo-Jin, Choi, Yun-Jung, Gurunathan, Sangiliyandi, Kim, Jin-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586103/
https://www.ncbi.nlm.nih.gov/pubmed/26319214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586103/
https://www.ncbi.nlm.nih.gov/pubmed/26319214

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