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Assessing FOXO1A as a Potential Susceptibility Locus for Type 2 Diabetes and Obesity in American Indians
OBJECTIVE: A prior genome-wide association study (GWAS) in Pima Indians identified variation within FOXO1A that modestly associated with early-onset (onset age<25years) type 2 diabetes (T2D). FOXO1A encodes the forkhead transcription factor involved in pancreatic β-cell growth and hypothalamic en...
Autores principales: | Muller, Yunhua L., Hanson, Robert L., Wiessner, Gregory, Nieboer, Lori, Kobes, Sayuko, Piaggi, Paolo, AbdusSamad, Mahdi, Okani, Chidinma, Knowler, William C., Bogardus, Clifton, Baier, Leslie J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586407/ https://www.ncbi.nlm.nih.gov/pubmed/26337673 http://dx.doi.org/10.1002/oby.21236 |
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