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The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity

Indoleamine 2, 3-dioxygenase (IDO) is the first and rate limiting catabolic enzyme in the degradation pathway of the essential amino acid tryptophan. By cleaving the aromatic indole ring of tryptophan, IDO initiates the production of a variety of tryptophan degradation products called “kynurenines”...

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Detalles Bibliográficos
Autores principales:	Mbongue, Jacques C., Nicholas, Dequina A., Torrez, Timothy W., Kim, Nan-Sun, Firek, Anthony F., Langridge, William H.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586474/ https://www.ncbi.nlm.nih.gov/pubmed/26378585 http://dx.doi.org/10.3390/vaccines3030703

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