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Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle

Smooth muscle myosin (SMM) light chain kinase (MLCK) phosphorylates SMM, thereby activating the ATPase activity required for muscle contraction. The abundance of active MLCK, which is tightly associated with the contractile apparatus, is low relative to that of SMM. SMM phosphorylation is rapid desp...

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Detalles Bibliográficos
Autores principales:	Hong, Feng, Brizendine, Richard K., Carter, Michael S., Alcala, Diego B., Brown, Avery E., Chattin, Amy M., Haldeman, Brian D., Walsh, Michael P., Facemyer, Kevin C., Baker, Josh E., Cremo, Christine R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586593/ https://www.ncbi.nlm.nih.gov/pubmed/26415568 http://dx.doi.org/10.1085/jgp.201511483

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