Blocking the Wnt/β-Catenin Pathway by Lentivirus-Mediated Short Hairpin RNA Targeting β-Catenin Gene Suppresses Silica-Induced Lung Fibrosis in Mice

Silicosis is a form of occupational lung disease caused by inhalation of crystalline silica dust. While the pathogenesis of silicosis is not clearly understood, the Wnt/β-catenin signaling pathway is thought to play a major role in lung fibrosis. To explore the role of Wnt/β-catenin pathway in silic...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Dai, Wujing, Wang, Yanrang, Gu, Qing, Yang, Deyi, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586640/
https://www.ncbi.nlm.nih.gov/pubmed/26340635
http://dx.doi.org/10.3390/ijerph120910739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586640/
https://www.ncbi.nlm.nih.gov/pubmed/26340635
http://dx.doi.org/10.3390/ijerph120910739

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