mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis

Neutrophils use chemotaxis to locate invading bacteria. Adenosine triphosphate (ATP) release and autocrine purinergic signaling via P2Y2 receptors at the front and A2a receptors at the back of cells regulate chemotaxis. Here, we examined the intracellular mechanisms that control these opposing signa...

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Detalles Bibliográficos
Autores principales: Bao, Yi, Ledderose, Carola, Graf, Amelie F., Brix, Bianca, Birsak, Theresa, Lee, Albert, Zhang, Jingping, Junger, Wolfgang G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586745/
https://www.ncbi.nlm.nih.gov/pubmed/26416965
http://dx.doi.org/10.1083/jcb.201503066

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