Not All Next Generation Sequencing Diagnostics are Created Equal: Understanding the Nuances of Solid Tumor Assay Design for Somatic Mutation Detection

The molecular characterization of tumors using next generation sequencing (NGS) is an emerging diagnostic tool that is quickly becoming an integral part of clinical decision making. Cancer genomic profiling involves significant challenges including DNA quality and quantity, tumor heterogeneity, and...

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Detalles Bibliográficos
Autores principales: Gray, Phillip N., Dunlop, Charles L.M., Elliott, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586770/
https://www.ncbi.nlm.nih.gov/pubmed/26193321
http://dx.doi.org/10.3390/cancers7030837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586770/
https://www.ncbi.nlm.nih.gov/pubmed/26193321
http://dx.doi.org/10.3390/cancers7030837

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