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Hedgehog Signaling in the Maintenance of Cancer Stem Cells

Cancer stem cells (CSCs) represent a rare population of cells with the capacity to self-renew and give rise to heterogeneous cell lineages within a tumour. Whilst the mechanisms underlying the regulation of CSCs are poorly defined, key developmental signaling pathways required for normal stem and pr...

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Detalles Bibliográficos
Autores principales:	Cochrane, Catherine R., Szczepny, Anette, Watkins, D. Neil, Cain, Jason E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586784/ https://www.ncbi.nlm.nih.gov/pubmed/26270676 http://dx.doi.org/10.3390/cancers7030851

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