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Non-Canonical Hh Signaling in Cancer—Current Understanding and Future Directions
As a major regulatory pathway for embryonic development and tissue patterning, hedgehog signaling is not active in most adult tissues, but is reactivated in a number of human cancer types. A major milestone in hedgehog signaling in cancer is the Food and Drug Administration (FDA) approval of a smoot...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586790/ https://www.ncbi.nlm.nih.gov/pubmed/26343727 http://dx.doi.org/10.3390/cancers7030857 |