Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review

Metastatic malignant tumors that originate from occult primaries are defined as “cancers of unknown origin.” We herein present the case of a 59-year-old man who presented with small bowel perforation secondary to metastatic adenocarcinoma of an unknown primary site. Imaging exhibited two pulmonary n...

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Autores principales: Alkabie, Samir, Bello, Brian, Martinez, Roberto F., Geis, W. Peter, Ballo, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586912/
https://www.ncbi.nlm.nih.gov/pubmed/26425638
http://dx.doi.org/10.1177/2324709615577415
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author Alkabie, Samir
Bello, Brian
Martinez, Roberto F.
Geis, W. Peter
Ballo, Michael S.
author_facet Alkabie, Samir
Bello, Brian
Martinez, Roberto F.
Geis, W. Peter
Ballo, Michael S.
author_sort Alkabie, Samir
collection PubMed
description Metastatic malignant tumors that originate from occult primaries are defined as “cancers of unknown origin.” We herein present the case of a 59-year-old man who presented with small bowel perforation secondary to metastatic adenocarcinoma of an unknown primary site. Imaging exhibited two pulmonary nodules, neither of which was dominant, along with mediastinal and retroperitoneal lymphadenopathy. Immunohistochemical profiling of the small bowel biopsy specimens revealed the tumor was most likely pulmonary in origin.
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spelling pubmed-45869122015-09-30 Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review Alkabie, Samir Bello, Brian Martinez, Roberto F. Geis, W. Peter Ballo, Michael S. J Investig Med High Impact Case Rep Article Metastatic malignant tumors that originate from occult primaries are defined as “cancers of unknown origin.” We herein present the case of a 59-year-old man who presented with small bowel perforation secondary to metastatic adenocarcinoma of an unknown primary site. Imaging exhibited two pulmonary nodules, neither of which was dominant, along with mediastinal and retroperitoneal lymphadenopathy. Immunohistochemical profiling of the small bowel biopsy specimens revealed the tumor was most likely pulmonary in origin. SAGE Publications 2015-03-23 /pmc/articles/PMC4586912/ /pubmed/26425638 http://dx.doi.org/10.1177/2324709615577415 Text en © 2015 American Federation for Medical Research http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Article
Alkabie, Samir
Bello, Brian
Martinez, Roberto F.
Geis, W. Peter
Ballo, Michael S.
Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title_full Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title_fullStr Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title_full_unstemmed Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title_short Metastatic Adenocarcinoma of Unknown Origin Presenting as Small Bowel Perforation: A Case Report and Literature Review
title_sort metastatic adenocarcinoma of unknown origin presenting as small bowel perforation: a case report and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586912/
https://www.ncbi.nlm.nih.gov/pubmed/26425638
http://dx.doi.org/10.1177/2324709615577415
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