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Optimizing the design of protein nanoparticles as carriers for vaccine applications

Successful vaccine development remains a huge challenge for infectious diseases such as malaria, HIV and influenza. As a novel way to present antigenic epitopes to the immune system, we have developed icosahedral self-assembling protein nanoparticles (SAPNs) to serve as a prototypical vaccine platfo...

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Detalles Bibliográficos
Autores principales: Doll, Tais A.P.F., Neef, Tobias, Duong, Nha, Lanar, David E., Ringler, Philippe, Müller, Shirley A., Burkhard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587294/
https://www.ncbi.nlm.nih.gov/pubmed/26051652
http://dx.doi.org/10.1016/j.nano.2015.05.003