Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL–C levels in a latvian population

BACKGROUND: Familial hypercholesterolemia (FH) is one of the commonest monogenic disorders, predominantly inherited as an autosomal dominant trait. When untreated, it results in early coronary heart disease. The vast majority of FH remains undiagnosed in Latvia. The identification and early treatmen...

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Detalles Bibliográficos
Autores principales: Radovica-Spalvina, Ilze, Latkovskis, Gustavs, Silamikelis, Ivars, Fridmanis, Davids, Elbere, Ilze, Ventins, Karlis, Ozola, Guna, Erglis, Andrejs, Klovins, Janis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587402/
https://www.ncbi.nlm.nih.gov/pubmed/26415676
http://dx.doi.org/10.1186/s12881-015-0230-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587402/
https://www.ncbi.nlm.nih.gov/pubmed/26415676
http://dx.doi.org/10.1186/s12881-015-0230-x

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