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Delivering Agents Locally into Articular Cartilage by Intense MHz Ultrasound
There is no cure for osteoarthritis. Current drug delivery relies on systemic delivery or injections into the joint. Because articular cartilage (AC) degeneration can be local and drug exposure outside the lesion can cause adverse effects, localized drug delivery could permit new drug treatment stra...
Autores principales: | Nieminen, Heikki J., Ylitalo, Tuomo, Suuronen, Jussi-Petteri, Rahunen, Krista, Salmi, Ari, Saarakkala, Simo, Serimaa, Ritva, Hæggström, Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587538/ https://www.ncbi.nlm.nih.gov/pubmed/25922135 http://dx.doi.org/10.1016/j.ultrasmedbio.2015.03.025 |
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