Epithelial to Mesenchymal Transition induces cell cycle arrest and parenchymal damage in renal fibrosis

Kidney fibrosis is marked by an epithelial–to–mesenchymal transition (EMT) by tubular epithelial cells (TECs). Here we find that during renal fibrosis TECs acquire a partial EMT program during which they remain associated with their basement membrane and express markers of both epithelial and mesenc...

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Detalles Bibliográficos
Autores principales: Lovisa, Sara, LeBleu, Valerie S., Tampe, Björn, Sugimoto, Hikaru, Vadnagara, Komal, Carstens, Julienne L., Wu, Chia–Chin, Hagos, Yohannes, Burckhardt, Birgitta C., Pentcheva–Hoang, Tsvetelina, Nischal, Hersharan, Allison, James P., Zeisberg, Michael, Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587560/
https://www.ncbi.nlm.nih.gov/pubmed/26236991
http://dx.doi.org/10.1038/nm.3902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587560/
https://www.ncbi.nlm.nih.gov/pubmed/26236991
http://dx.doi.org/10.1038/nm.3902

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