Validation and utilization of a TFE3 break-apart FISH assay for Xp11.2 translocation renal cell carcinoma and alveolar soft part sarcoma

BACKGROUND: Xp11.2 or TFE3 translocation renal cell carcinomas (RCC) and alveolar soft part sarcoma (ASPS) are characterized by chromosome translocations involving the Xp11.2 breakpoint resulting in transcription factor TFE3 gene fusions. The most common translocations documented in TFE3 RCCs are t(...

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Detalles Bibliográficos
Autores principales: Pradhan, Dinesh, Roy, Somak, Quiroga-Garza, Gabriela, Cieply, Kathleen, Mahaffey, Alyssa L., Bastacky, Sheldon, Dhir, Rajiv, Parwani, Anil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587681/
https://www.ncbi.nlm.nih.gov/pubmed/26415891
http://dx.doi.org/10.1186/s13000-015-0412-z

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