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Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

BACKGROUND: Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These characteristics correlate with a distinct nuclear architecture, epigenetic signatures enriched for active chromatin marks and hyperdynamic binding of structural...

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Detalles Bibliográficos
Autores principales:	Mattout, Anna, Aaronson, Yair, Sailaja, Badi Sri, Raghu Ram, Edupuganti V., Harikumar, Arigela, Mallm, Jan-Philipp, Sim, Kae Hwan, Nissim-Rafinia, Malka, Supper, Emmanuelle, Singh, Prim B., Sze, Siu Kwan, Gasser, Susan M., Rippe, Karsten, Meshorer, Eran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587738/ https://www.ncbi.nlm.nih.gov/pubmed/26415775 http://dx.doi.org/10.1186/s13059-015-0760-8

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