Sepsis-induced selective parvalbumin interneuron phenotype loss and cognitive impairments may be mediated by NADPH oxidase 2 activation in mice

BACKGROUND: Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction caused by many pathological events, including neuroinflammation and oxidative stress damage. Increasing evidence suggests that parvalbumin (PV) interneurons play a key role in the cognitive process, whereas the dysfunc...

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Detalles Bibliográficos
Autores principales: Ji, Mu-Huo, Qiu, Li-Li, Tang, Hui, Ju, Ling-Sha, Sun, Xiao-Ru, Zhang, Hui, Jia, Min, Zuo, Zhi-Yi, Shen, Jin-Chun, Yang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587802/
https://www.ncbi.nlm.nih.gov/pubmed/26416717
http://dx.doi.org/10.1186/s12974-015-0401-x

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