Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics

BACKGROUND: Compared to engineering or physics problems, dynamical models in quantitative biology typically depend on a relatively large number of parameters. Progress in developing mathematics to manipulate such multi-parameter models and so enable their efficient interplay with experiments has bee...

Descripción completa

Detalles Bibliográficos
Autores principales: Nienałtowski, Karol, Włodarczyk, Michał, Lipniacki, Tomasz, Komorowski, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587803/
https://www.ncbi.nlm.nih.gov/pubmed/26415494
http://dx.doi.org/10.1186/s12918-015-0205-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587803/
https://www.ncbi.nlm.nih.gov/pubmed/26415494
http://dx.doi.org/10.1186/s12918-015-0205-8

Ejemplares similares