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Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics
BACKGROUND: Compared to engineering or physics problems, dynamical models in quantitative biology typically depend on a relatively large number of parameters. Progress in developing mathematics to manipulate such multi-parameter models and so enable their efficient interplay with experiments has bee...
Autores principales: | Nienałtowski, Karol, Włodarczyk, Michał, Lipniacki, Tomasz, Komorowski, Michał |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587803/ https://www.ncbi.nlm.nih.gov/pubmed/26415494 http://dx.doi.org/10.1186/s12918-015-0205-8 |
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