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Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

BACKGROUND: Many neurodegenerative diseases are associated with protein misfolding/aggregation. Treatments mitigating the effects of such common pathological processes, rather than disease-specific symptoms, therefore have general therapeutic potential. RESULTS: Here we report that the anti-epilepti...

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Detalles Bibliográficos
Autores principales:	Chen, Xi, McCueF, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587861/ https://www.ncbi.nlm.nih.gov/pubmed/26419537 http://dx.doi.org/10.1186/s13024-015-0046-3

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