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Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer

BACKGROUND: CpG hypermethylation in gene promoters is a frequent mechanism of tumor suppressor gene silencing in various types of cancers. It usually occurs at early steps of cancer progression and can be detected easily, giving rise to development of promising biomarkers for both detection and prog...

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Detalles Bibliográficos
Autores principales:	Sayar, Nilufer, Karahan, Gurbet, Konu, Ozlen, Bozkurt, Betul, Bozdogan, Onder, Yulug, Isik G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587865/ https://www.ncbi.nlm.nih.gov/pubmed/26421063 http://dx.doi.org/10.1186/s13148-015-0138-5

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