The role of fatty acids in insulin resistance

Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin resistance appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular b...

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Detalles Bibliográficos
Autores principales: Sears, Barry, Perry, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587882/
https://www.ncbi.nlm.nih.gov/pubmed/26415887
http://dx.doi.org/10.1186/s12944-015-0123-1
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author Sears, Barry
Perry, Mary
author_facet Sears, Barry
Perry, Mary
author_sort Sears, Barry
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description Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin resistance appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular basis for insulin resistance can be quite different in various organs. This review deals with various types of inflammatory inputs mediated by fatty acids, which affect the extent of insulin resistance in various organs.
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spelling pubmed-45878822015-09-30 The role of fatty acids in insulin resistance Sears, Barry Perry, Mary Lipids Health Dis Review Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin resistance appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular basis for insulin resistance can be quite different in various organs. This review deals with various types of inflammatory inputs mediated by fatty acids, which affect the extent of insulin resistance in various organs. BioMed Central 2015-09-29 /pmc/articles/PMC4587882/ /pubmed/26415887 http://dx.doi.org/10.1186/s12944-015-0123-1 Text en © Sears and Perry. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Sears, Barry
Perry, Mary
The role of fatty acids in insulin resistance
title The role of fatty acids in insulin resistance
title_full The role of fatty acids in insulin resistance
title_fullStr The role of fatty acids in insulin resistance
title_full_unstemmed The role of fatty acids in insulin resistance
title_short The role of fatty acids in insulin resistance
title_sort role of fatty acids in insulin resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587882/
https://www.ncbi.nlm.nih.gov/pubmed/26415887
http://dx.doi.org/10.1186/s12944-015-0123-1
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