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Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells

INTRODUCTION: The prevalence of renal fibrosis is higher in older than in younger individuals. Through paracrine activity, bone marrow mesenchymal stem cell-derived microvesicles (BM-MSC-MVs) influence the process of renal fibrosis. Differences in microRNA (miRNA) expression of BM-MSC-MVs that corre...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Fu, Bo, Sun, Xuefeng, Li, Diangeng, Huang, Qi, Zhao, Weihong, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587922/
https://www.ncbi.nlm.nih.gov/pubmed/26415502
http://dx.doi.org/10.1186/s13287-015-0179-x