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Apamin Boosting of Synaptic Potentials in Ca(V)2.3 R-Type Ca(2+) Channel Null Mice

SK2- and K(V)4.2-containing K(+) channels modulate evoked synaptic potentials in CA1 pyramidal neurons. Each is coupled to a distinct Ca(2+) source that provides Ca(2+)-dependent feedback regulation to limit AMPA receptor (AMPAR)- and NMDA receptor (NMDAR)-mediated postsynaptic depolarization. SK2-c...

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Detalles Bibliográficos
Autores principales: Wang, Kang, Kelley, Melissa H., Wu, Wendy W., Adelman, John P., Maylie, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587947/
https://www.ncbi.nlm.nih.gov/pubmed/26418566
http://dx.doi.org/10.1371/journal.pone.0139332

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