Cargando…
Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently
In renal failure, the systemic accumulation of uremic waste products is strongly associated with the development of a chronic inflammatory state. Here, the effect of cationic uremic toxins on the release of inflammatory cytokines and endothelin-1 (ET-1) was investigated in conditionally immortalized...
Autores principales: | Schophuizen, Carolien M. S., Hoenderop, Joost G. J., Masereeuw, Rosalinde, van den Heuvel, Lambert P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588034/ https://www.ncbi.nlm.nih.gov/pubmed/26132391 http://dx.doi.org/10.3390/cells4030234 |
Ejemplares similares
-
The Uremic Toxin Indoxyl Sulfate Accelerates Senescence in Kidney Proximal Tubule Cells
por: Yang, Yi, et al.
Publicado: (2023) -
Bioengineered kidney tubules efficiently excrete uremic toxins
por: Jansen, J., et al.
Publicado: (2016) -
Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
por: Faria, João, et al.
Publicado: (2023) -
Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations
por: Jansen, J., et al.
Publicado: (2015) -
Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1β Production in Kidney Proximal Tubule Cells
por: Mihajlovic, Milos, et al.
Publicado: (2021)