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Optodynamic simulation of β-adrenergic receptor signalling

Optogenetics has provided a revolutionary approach to dissecting biological phenomena. However, the generation and use of optically active GPCRs in these contexts is limited and it is unclear how well an opsin-chimera GPCR might mimic endogenous receptor activity. Here we show that a chimeric rhodop...

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Detalles Bibliográficos
Autores principales:	Siuda, Edward R., McCall, Jordan G., Al-Hasani, Ream, Shin, Gunchul, Il Park, Sung, Schmidt, Martin J., Anderson, Sonya L., Planer, William J., Rogers, John A., Bruchas, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588095/ https://www.ncbi.nlm.nih.gov/pubmed/26412387 http://dx.doi.org/10.1038/ncomms9480

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