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New drug target in protozoan parasites: the role of thioredoxin reductase

Amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. It is treated primarily with metronidazole, which has adverse side effects, is mutagenic and carcinogenic, and emergence of resistance is an increasing concern. Unfortunately, better the...

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Detalles Bibliográficos
Autores principales: Andrade, Rosa M., Reed, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588103/
https://www.ncbi.nlm.nih.gov/pubmed/26483758
http://dx.doi.org/10.3389/fmicb.2015.00975