Cargando…
New drug target in protozoan parasites: the role of thioredoxin reductase
Amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. It is treated primarily with metronidazole, which has adverse side effects, is mutagenic and carcinogenic, and emergence of resistance is an increasing concern. Unfortunately, better the...
Autores principales: | Andrade, Rosa M., Reed, Sharon L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588103/ https://www.ncbi.nlm.nih.gov/pubmed/26483758 http://dx.doi.org/10.3389/fmicb.2015.00975 |
Ejemplares similares
-
Auranofin Resistance in Toxoplasma gondii Decreases the Accumulation of Reactive Oxygen Species but Does Not Target Parasite Thioredoxin Reductase
por: Ma, Christopher I., et al.
Publicado: (2021) -
Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors
por: Kelso, Andrew A., et al.
Publicado: (2017) -
Thioredoxin Reductase Is Involved in Development and Pathogenicity in Fusarium graminearum
por: Fan, Xinyue, et al.
Publicado: (2019) -
Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites
por: Varikuti, Sanjay, et al.
Publicado: (2018) -
Cysteine proteases in protozoan parasites
por: Siqueira-Neto, Jair L., et al.
Publicado: (2018)