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Multi-Facial, Non-Peptidic α-Helix Mimetics

α-Helices often recognize their target proteins at protein–protein interfaces through more than one recognition face. This review describes the state-of-the-art in the design of non-peptidic α-helix mimetics that reproduce functionality from multiple faces of an α-helix.

Detalles Bibliográficos
Autores principales: Lanning, Maryanna E., Fletcher, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588149/
https://www.ncbi.nlm.nih.gov/pubmed/26404384
http://dx.doi.org/10.3390/biology4030540