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Multi-Facial, Non-Peptidic α-Helix Mimetics
α-Helices often recognize their target proteins at protein–protein interfaces through more than one recognition face. This review describes the state-of-the-art in the design of non-peptidic α-helix mimetics that reproduce functionality from multiple faces of an α-helix.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588149/ https://www.ncbi.nlm.nih.gov/pubmed/26404384 http://dx.doi.org/10.3390/biology4030540 |