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Homeostasis as the Mechanism of Evolution

Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic, intergenerational, diachronic (across-time) mech...

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Detalles Bibliográficos
Autor principal: Torday, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588151/
https://www.ncbi.nlm.nih.gov/pubmed/26389962
http://dx.doi.org/10.3390/biology4030573
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author Torday, John S.
author_facet Torday, John S.
author_sort Torday, John S.
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description Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic, intergenerational, diachronic (across-time) mechanism for the maintenance, perpetuation and modification of physiologic structure and function. The integral relationships generated by cell-cell signaling for the mechanisms of embryogenesis, physiology and repair provide the needed insight to the scale-free universality of the homeostatic principle, offering a novel opportunity for a Systems approach to Biology. Starting with the inception of life itself, with the advent of reproduction during meiosis and mitosis, moving forward both ontogenetically and phylogenetically through the evolutionary steps involved in adaptation to an ever-changing environment, Biology and Evolution Theory need no longer default to teleology.
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spelling pubmed-45881512015-10-08 Homeostasis as the Mechanism of Evolution Torday, John S. Biology (Basel) Hypothesis Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic, intergenerational, diachronic (across-time) mechanism for the maintenance, perpetuation and modification of physiologic structure and function. The integral relationships generated by cell-cell signaling for the mechanisms of embryogenesis, physiology and repair provide the needed insight to the scale-free universality of the homeostatic principle, offering a novel opportunity for a Systems approach to Biology. Starting with the inception of life itself, with the advent of reproduction during meiosis and mitosis, moving forward both ontogenetically and phylogenetically through the evolutionary steps involved in adaptation to an ever-changing environment, Biology and Evolution Theory need no longer default to teleology. MDPI 2015-09-15 /pmc/articles/PMC4588151/ /pubmed/26389962 http://dx.doi.org/10.3390/biology4030573 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Hypothesis
Torday, John S.
Homeostasis as the Mechanism of Evolution
title Homeostasis as the Mechanism of Evolution
title_full Homeostasis as the Mechanism of Evolution
title_fullStr Homeostasis as the Mechanism of Evolution
title_full_unstemmed Homeostasis as the Mechanism of Evolution
title_short Homeostasis as the Mechanism of Evolution
title_sort homeostasis as the mechanism of evolution
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588151/
https://www.ncbi.nlm.nih.gov/pubmed/26389962
http://dx.doi.org/10.3390/biology4030573
work_keys_str_mv AT tordayjohns homeostasisasthemechanismofevolution