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cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-β-Induced Synapse Damage
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate in Parkinson’s disease, also caused synapse d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588152/ https://www.ncbi.nlm.nih.gov/pubmed/26389963 http://dx.doi.org/10.3390/biology4030591 |