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Contribution of Epigenetic Modifications to the Decline in Transgene Expression from Plasmid DNA in Mouse Liver

Short-term expression of transgenes is one of the problems frequently associated with non-viral in vivo gene transfer. To obtain experimental evidence for the design of sustainable transgene expression systems, the contribution of epigenetic modifications to the decline in transgene expression needs...

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Detalles Bibliográficos
Autores principales:	Zang, Lei, Nishikawa, Makiya, Ando, Mitsuru, Takahashi, Yuki, Takakura, Yoshinobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588195/ https://www.ncbi.nlm.nih.gov/pubmed/26262639 http://dx.doi.org/10.3390/pharmaceutics7030199

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