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Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying
In this study, two types of biodegradable polycation (PAsp(DET) homopolymer and PEG-PAsp(DET) copolymer) were applied as vectors for inhalable dry gene powders prepared by spray freeze drying (SFD). The prepared dry gene powders had spherical and porous structures with a 5~10-μm diameter, and the in...
Autores principales: | Okuda, Tomoyuki, Suzuki, Yumiko, Kobayashi, Yuko, Ishii, Takehiko, Uchida, Satoshi, Itaka, Keiji, Kataoka, Kazunori, Okamoto, Hirokazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588198/ https://www.ncbi.nlm.nih.gov/pubmed/26343708 http://dx.doi.org/10.3390/pharmaceutics7030233 |
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