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Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling
INTRODUCTION: Ischemic stroke, a major cause of mortality, is frequently accompanied by life-threatening cerebral edema. Aquaporin-4 (Aqp4), an astrocytic transmembrane water channel, is an important molecular contributor to cerebral edema formation. Past studies of Aqp4 expression and localization...
Autores principales: | Stokum, Jesse A., Mehta, Rupal I., Ivanova, Svetlana, Yu, Edward, Gerzanich, Volodymyr, Simard, J. Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588314/ https://www.ncbi.nlm.nih.gov/pubmed/26419740 http://dx.doi.org/10.1186/s40478-015-0239-6 |
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