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Data in support of quantitative proteomics to identify potential virulence regulators in Paracoccidioides brasiliensis isolates

Paracoccidioides genus are the etiologic agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and...

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Detalles Bibliográficos
Autores principales: Tashima, Alexandre Keiji, Castilho, Daniele Gonçalves, Chaves, Alison Felipe Alencar, Xander, Patricia, Zelanis, André, Batista, Wagner Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588363/
https://www.ncbi.nlm.nih.gov/pubmed/26501084
http://dx.doi.org/10.1016/j.dib.2015.09.001
Descripción
Sumario:Paracoccidioides genus are the etiologic agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and virulent isolates [1]. The protein compositions of two isolates of the Pb18 strain showing distinct infection profiles were quantitatively assessed by stable isotopic dimethyl labeling and proteomic analysis. The mass spectrometry and the analysis dataset have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifier PXD000804.