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Membrane lipids and the endoplasmic reticulum unfolded protein response: An interesting relationship
The unfolded protein response of the endoplasmic reticulum (UPR(ER)) is a conserved signaling circuit that ensures ER protein homeostasis (proteostasis). In the UPR(ER) of higher eukaryotes, multiple sensors cooperatively perceive proteostatic disturbances in the ER lumen and induce downstream adapt...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588386/ https://www.ncbi.nlm.nih.gov/pubmed/26430548 http://dx.doi.org/10.4161/21624046.2014.962405 |