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Discovery of Genetic Variants of the Kinases That Activate Tenofovir in a Compartment-specific Manner

Tenofovir (TFV) is used in combination with other antiretroviral drugs for human immunodeficiency virus (HIV) treatment and prevention. TFV requires two phosphorylation steps to become pharmacologically active; however, the kinases that activate TFV in cells and tissues susceptible to HIV infection...

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Detalles Bibliográficos
Autores principales:	Lade, Julie M., To, Elaine E., Hendrix, Craig W., Bumpus, Namandjé N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588390/ https://www.ncbi.nlm.nih.gov/pubmed/26501112 http://dx.doi.org/10.1016/j.ebiom.2015.07.008

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