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The Helicobacter Eradication Aspirin Trial (HEAT): A Large Simple Randomised Controlled Trial Using Novel Methodology in Primary Care
BACKGROUND: Clinical trials measuring the effect of an intervention on clinical outcomes are more influential than those investigating surrogate measures but are costly. We developed methods to reduce costs substantially by using existing data in primary care systems, to ask whether Helicobacter pyl...
Autores principales: | Dumbleton, Jennifer S., Avery, Anthony J., Coupland, Carol, Hobbs, F.D. Richard, Kendrick, Denise, Moore, Michael V., Morris, Clive, Rubin, Greg P., Smith, Murray D., Stevenson, Diane J., Hawkey, Chris J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588401/ https://www.ncbi.nlm.nih.gov/pubmed/26501118 http://dx.doi.org/10.1016/j.ebiom.2015.07.012 |
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