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Absence of somatic mutations of the mTOR gene in differentiated thyroid cancer

Thyroid cancer is the most common endocrine malignancy with increasing incidence. Mammalian target of rapamycin (mTOR) is an important downstream mediator of phosphatidylinositol 3-kinase (PI3K/Akt) signaling and regulates cell growth, apoptosis and metabolism. The mTOR gene is frequently mutated in...

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Detalles Bibliográficos
Autores principales:	Murugan, Avaniyapuram Kannan, Humudh, Eman A., Qasem, Ebtesam, Al-Hindi, Hindi, Almohanna, Mai, Hassan, Zeinab Korany, Alzahrani, Ali S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588405/ https://www.ncbi.nlm.nih.gov/pubmed/26504747 http://dx.doi.org/10.1016/j.mgene.2015.08.005

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