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Ellagic acid, a polyphenolic compound, selectively induces ROS-mediated apoptosis in cancerous B-lymphocytes of CLL patients by directly targeting mitochondria

To investigate the effects ofellagic acid (EA) on the cytotoxicity, B-lymphocytes isolated from CLL patients and healthy individuals. Flow cytometric assay was used to measure the percentage of apoptosis versus necrosis, intracellular active oxygen radicals (ROS), mitochondrial membrane potential (M...

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Detalles Bibliográficos
Autores principales:	Salimi, Ahmad, Roudkenar, Mehryar Habibi, Sadeghi, Leila, Mohseni, Alireza, Seydi, Enayatollah, Pirahmadi, Nahal, Pourahmad, Jalal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588415/ https://www.ncbi.nlm.nih.gov/pubmed/26418626 http://dx.doi.org/10.1016/j.redox.2015.08.021

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