HIV-1 Reservoir Association with Immune Activation

In this issue of EBioMedicine, Ruggiero and colleagues describe immune activation biomarkers associated with the size of the HIV reservoir in a carefully designed cross-sectional study. The cohort consists of a homogeneous sample of HIV-1-infected patients with long-term plasma HIV-1 RNA suppression...

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Detalles Bibliográficos
Autor principal: Vallejo, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588428/
https://www.ncbi.nlm.nih.gov/pubmed/26501094
http://dx.doi.org/10.1016/j.ebiom.2015.08.025
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author Vallejo, Alejandro
author_facet Vallejo, Alejandro
author_sort Vallejo, Alejandro
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description In this issue of EBioMedicine, Ruggiero and colleagues describe immune activation biomarkers associated with the size of the HIV reservoir in a carefully designed cross-sectional study. The cohort consists of a homogeneous sample of HIV-1-infected patients with long-term plasma HIV-1 RNA suppression under antiretroviral treatment (ART). It is crucial to explore the potential utility of biomarkers that are easier (less labor intensive, less expensive) to measure than integrated HIV DNA load, in order to quickly and accurately quantify cellular reservoirs of HIV.
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spelling pubmed-45884282015-10-23 HIV-1 Reservoir Association with Immune Activation Vallejo, Alejandro EBioMedicine Commentary In this issue of EBioMedicine, Ruggiero and colleagues describe immune activation biomarkers associated with the size of the HIV reservoir in a carefully designed cross-sectional study. The cohort consists of a homogeneous sample of HIV-1-infected patients with long-term plasma HIV-1 RNA suppression under antiretroviral treatment (ART). It is crucial to explore the potential utility of biomarkers that are easier (less labor intensive, less expensive) to measure than integrated HIV DNA load, in order to quickly and accurately quantify cellular reservoirs of HIV. Elsevier 2015-08-16 /pmc/articles/PMC4588428/ /pubmed/26501094 http://dx.doi.org/10.1016/j.ebiom.2015.08.025 Text en © 2015 The Author. Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Vallejo, Alejandro
HIV-1 Reservoir Association with Immune Activation
title HIV-1 Reservoir Association with Immune Activation
title_full HIV-1 Reservoir Association with Immune Activation
title_fullStr HIV-1 Reservoir Association with Immune Activation
title_full_unstemmed HIV-1 Reservoir Association with Immune Activation
title_short HIV-1 Reservoir Association with Immune Activation
title_sort hiv-1 reservoir association with immune activation
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588428/
https://www.ncbi.nlm.nih.gov/pubmed/26501094
http://dx.doi.org/10.1016/j.ebiom.2015.08.025
work_keys_str_mv AT vallejoalejandro hiv1reservoirassociationwithimmuneactivation

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