Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation()

OBJECTIVE: Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces adaptations in the mesolimbic dopamine system and has a myriad of long-term beneficial...

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Detalles Bibliográficos
Autores principales: Obici, Silvana, Magrisso, I. Jack, Ghazarian, Armen S., Shirazian, Alireza, Miller, Jonas R., Loyd, Christine M., Begg, Denovan P., Krawczewski Carhuatanta, Kimberly A., Haas, Michael K., Davis, Jon F., Woods, Stephen C., Sandoval, Darleen A., Seeley, Randy J., Goodyear, Laurie J., Pothos, Emmanuel N., Mul, Joram D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588435/
https://www.ncbi.nlm.nih.gov/pubmed/26500841
http://dx.doi.org/10.1016/j.molmet.2015.07.003

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