Does pyridoxine control behavioral symptoms in adult patients treated with levetiracetam? Case series from UAE()

Behavioral symptoms are known side effects of levetiracetam. Previous case series in children and adolescents have demonstrated the potential effect of pyridoxine in ameliorating these symptoms. We retrospectively reviewed the charts of 51 patients treated with pyridoxine to control agitation and ir...

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Detalles Bibliográficos
Autores principales: Alsaadi, Taoufik, El Hammasi, Khadija, Shahrour, Tarek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588452/
https://www.ncbi.nlm.nih.gov/pubmed/26543816
http://dx.doi.org/10.1016/j.ebcr.2015.08.003
Descripción
Sumario:Behavioral symptoms are known side effects of levetiracetam. Previous case series in children and adolescents have demonstrated the potential effect of pyridoxine in ameliorating these symptoms. We retrospectively reviewed the charts of 51 patients treated with pyridoxine to control agitation and irritability following the introduction of levetiracetam. These symptoms were relieved in 34 patients (66.6%). Seventeen patients did not appear to benefit from this supplementation. This preliminary study suggests that pyridoxine might be an effective option across all ages for patients suffering from levetiracetam-induced behavioral side effects.

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