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Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up

OBJECTIVES: Reoperation rates for meniscal allograft surgery (MAT) are high with a 70% survival rate at 10 years. The indications and findings for secondary surgery are not well characterized. The purpose of this study is to quantify the percentage of transplants requiring a re-operation, to charact...

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Autores principales: McCormick, Francis, Harris, Joshua David, Frank, Rachel M., Hussey, Kristen Elizabeth, Wilson, Hillary, Gupta, Anil Kumar, Abrams, Geoffrey D., Bach, Bernard R., Cole, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588481/
http://dx.doi.org/10.1177/2325967114S00003
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author McCormick, Francis
Harris, Joshua David
Frank, Rachel M.
Hussey, Kristen Elizabeth
Wilson, Hillary
Gupta, Anil Kumar
Abrams, Geoffrey D.
Bach, Bernard R.
Cole, Brian J.
author_facet McCormick, Francis
Harris, Joshua David
Frank, Rachel M.
Hussey, Kristen Elizabeth
Wilson, Hillary
Gupta, Anil Kumar
Abrams, Geoffrey D.
Bach, Bernard R.
Cole, Brian J.
author_sort McCormick, Francis
collection PubMed
description OBJECTIVES: Reoperation rates for meniscal allograft surgery (MAT) are high with a 70% survival rate at 10 years. The indications and findings for secondary surgery are not well characterized. The purpose of this study is to quantify the percentage of transplants requiring a re-operation, to characterize the operative findings, perform a survival analysis, and perform a case-control analysis if an early return to surgery is predictive of failure. METHODS: A retrospective review of prospectively collected data from a single-surgeon was performed. Inclusion period was 2003-2011.. The number of patients returning to the OR and the findings at surgery were recorded. A meniscal transplant survival curve, the duration between transplantation and return to OR, and an odds-ratio of risk for failure for those requiring a re-operation in the perioperative period were calculated. RESULTS: Two hundred patients underwent a MAT during the study period. 38% were isolated; 62% had concomitant procedures. Sixty-four (32%) patients returned to the operating room, of which 38 (59%) were for a meniscal? debridement. The mean duration to secondary surgery was 21 months, with 73% within 2 years. One hundred seventy-two (86%) patients were evaluated at a mean 59 months (Range 24-118 months). Eight went on to require a revision MAT or total knee replacement (4.7%). Patients requiring secondary surgery within two years had an 8.4 odds-ratio for future failure (95% CI 1.6-43.4 p.007). CONCLUSION: In the largest consecutive series reported in the literature, meniscal allograft transplantation (MAT) has a 95% success rate a mean of approximately five years. There is a 32% reoperation rate, with meniscal debridement the most common secondary surgical treatment.
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spelling pubmed-45884812015-11-03 Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up McCormick, Francis Harris, Joshua David Frank, Rachel M. Hussey, Kristen Elizabeth Wilson, Hillary Gupta, Anil Kumar Abrams, Geoffrey D. Bach, Bernard R. Cole, Brian J. Orthop J Sports Med Article OBJECTIVES: Reoperation rates for meniscal allograft surgery (MAT) are high with a 70% survival rate at 10 years. The indications and findings for secondary surgery are not well characterized. The purpose of this study is to quantify the percentage of transplants requiring a re-operation, to characterize the operative findings, perform a survival analysis, and perform a case-control analysis if an early return to surgery is predictive of failure. METHODS: A retrospective review of prospectively collected data from a single-surgeon was performed. Inclusion period was 2003-2011.. The number of patients returning to the OR and the findings at surgery were recorded. A meniscal transplant survival curve, the duration between transplantation and return to OR, and an odds-ratio of risk for failure for those requiring a re-operation in the perioperative period were calculated. RESULTS: Two hundred patients underwent a MAT during the study period. 38% were isolated; 62% had concomitant procedures. Sixty-four (32%) patients returned to the operating room, of which 38 (59%) were for a meniscal? debridement. The mean duration to secondary surgery was 21 months, with 73% within 2 years. One hundred seventy-two (86%) patients were evaluated at a mean 59 months (Range 24-118 months). Eight went on to require a revision MAT or total knee replacement (4.7%). Patients requiring secondary surgery within two years had an 8.4 odds-ratio for future failure (95% CI 1.6-43.4 p.007). CONCLUSION: In the largest consecutive series reported in the literature, meniscal allograft transplantation (MAT) has a 95% success rate a mean of approximately five years. There is a 32% reoperation rate, with meniscal debridement the most common secondary surgical treatment. SAGE Publications 2014-12-02 /pmc/articles/PMC4588481/ http://dx.doi.org/10.1177/2325967114S00003 Text en © The Author(s) 2014 http://creativecommons.org/licenses/by-nc-nd/3.0/ This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For reprints and permission queries, please visit SAGE’s Web site at http://www.sagepub.com/journalsPermissions.nav.
spellingShingle Article
McCormick, Francis
Harris, Joshua David
Frank, Rachel M.
Hussey, Kristen Elizabeth
Wilson, Hillary
Gupta, Anil Kumar
Abrams, Geoffrey D.
Bach, Bernard R.
Cole, Brian J.
Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title_full Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title_fullStr Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title_full_unstemmed Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title_short Meniscal Allograft Transplantation Reoperation Rates, Operative Findings, and Survival Analysis: A Review of 200 Consecutive Transplants at Minimum Two-year Follow-up
title_sort meniscal allograft transplantation reoperation rates, operative findings, and survival analysis: a review of 200 consecutive transplants at minimum two-year follow-up
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588481/
http://dx.doi.org/10.1177/2325967114S00003
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