20 Years of unc-119 as a transgene marker

This fall marks 20 years since the cloning of unc-119 was reported. Despite having a strong phenotype that makes animals somewhat difficult to grow and handle, unc-119 mutant rescue has become one of the most frequently-used markers for C. elegans transformation. In this Commentary, I describe the h...

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Detalles Bibliográficos
Autor principal: Maduro, Morris F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588520/
https://www.ncbi.nlm.nih.gov/pubmed/26430568
http://dx.doi.org/10.1080/21624054.2015.1046031
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author Maduro, Morris F
author_facet Maduro, Morris F
author_sort Maduro, Morris F
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description This fall marks 20 years since the cloning of unc-119 was reported. Despite having a strong phenotype that makes animals somewhat difficult to grow and handle, unc-119 mutant rescue has become one of the most frequently-used markers for C. elegans transformation. In this Commentary, I describe the history of how unc-119 rescue traveled through the worm community, contributing to the development of transgene methods in C. elegans.
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spelling pubmed-45885202016-02-03 20 Years of unc-119 as a transgene marker Maduro, Morris F Worm Commentary This fall marks 20 years since the cloning of unc-119 was reported. Despite having a strong phenotype that makes animals somewhat difficult to grow and handle, unc-119 mutant rescue has become one of the most frequently-used markers for C. elegans transformation. In this Commentary, I describe the history of how unc-119 rescue traveled through the worm community, contributing to the development of transgene methods in C. elegans. Taylor & Francis 2015-06-19 /pmc/articles/PMC4588520/ /pubmed/26430568 http://dx.doi.org/10.1080/21624054.2015.1046031 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Commentary
Maduro, Morris F
20 Years of unc-119 as a transgene marker
title 20 Years of unc-119 as a transgene marker
title_full 20 Years of unc-119 as a transgene marker
title_fullStr 20 Years of unc-119 as a transgene marker
title_full_unstemmed 20 Years of unc-119 as a transgene marker
title_short 20 Years of unc-119 as a transgene marker
title_sort 20 years of unc-119 as a transgene marker
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588520/
https://www.ncbi.nlm.nih.gov/pubmed/26430568
http://dx.doi.org/10.1080/21624054.2015.1046031
work_keys_str_mv AT maduromorrisf 20yearsofunc119asatransgenemarker

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