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Characterization of DNA variants in the human kinome in breast cancer

Kinases play a key role in cancer biology, and serve as potential clinically useful targets for designing cancer therapies. We examined nucleic acid variations in the human kinome and several known cancer-related genes in breast cancer. DNA was extracted from fine needle biopsies of 73 primary breas...

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Detalles Bibliográficos
Autores principales:	Agarwal, Divyansh, Qi, Yuan, Jiang, Tingting, Liu, Xiuping, Shi, Weiwei, Wali, Vikram B., Turk, Benjamin, Ross, Jeffrey S, Fraser Symmans, W, Pusztai, Lajos, Hatzis, Christos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588561/ https://www.ncbi.nlm.nih.gov/pubmed/26420498 http://dx.doi.org/10.1038/srep14736

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