Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells

Ginkgo biloba leaf extract has been shown to increase the incidence in liver tumors in mice in a 2-year bioassay conducted by the National Toxicology Program. In this study, the DNA damaging effects of Ginkgo biloba leaf extract and many of its constituents were evaluated in human hepatic HepG2 cell...

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Detalles Bibliográficos
Autores principales: Zhang, Zhuhong, Chen, Si, Mei, Hu, Xuan, Jiekun, Guo, Xiaoqing, Couch, Letha, Dobrovolsky, Vasily N., Guo, Lei, Mei, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588569/
https://www.ncbi.nlm.nih.gov/pubmed/26419945
http://dx.doi.org/10.1038/srep14633

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