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Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue

Expression of mutant huntingtin (htt) protein has been shown to cause metabolic imbalance in animal models of Huntington disease (HD). The pathways involved are not fully understood but dysfunction of both the hypothalamus and brown adipose tissue (BAT) has been implicated. Here we show that targete...

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Detalles Bibliográficos
Autores principales:	Soylu-Kucharz, Rana, Adlesic, Natalie, Baldo, Barbara, Kirik, Deniz, Petersén, Åsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588570/ https://www.ncbi.nlm.nih.gov/pubmed/26419281 http://dx.doi.org/10.1038/srep14598

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