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Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer
In order to increase the therapeutic effect of doxorubicin (DOX) on bone metastases, a multifunctional micelle was developed by combining pH-sensitive characteristics with bone active targeting capacity. The DOX loaded micelle was self-assembled by using doxorubicin-poly (ethylene glycol)-alendronat...
Autores principales: | Ye, Wei-liang, Zhao, Yi-pu, Li, Huai-qiu, Na, Ren, Li, Fei, Mei, Qi-bing, Zhao, Ming-gao, Zhou, Si-yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588583/ https://www.ncbi.nlm.nih.gov/pubmed/26419507 http://dx.doi.org/10.1038/srep14614 |
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