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Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

Alzheimer’s disease (AD) is a neurodegenerative disease that causes progressive loss of cognitive functions, leading to dementia. Two types of lesions are found in AD brains: neurofibrillary tangles and senile plaques. The latter are composed mainly of the β-amyloid peptide (Aβ) generated by amyloid...

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Detalles Bibliográficos
Autores principales:	Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588712/ https://www.ncbi.nlm.nih.gov/pubmed/26500837 http://dx.doi.org/10.1016/j.fob.2015.09.002

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